The effects of moderate exercise on secretory IgA production in mice depends on dietary carbohydrate intake
نویسندگان
چکیده
Secretory immunoglobulin A (sIgA) is produced from intestinal mucosa and is essential in preventing infection. We analyzed the influence of moderate exercise on intestinal sIgA production and antioxidative function under different carbohydrate nutritional conditions. Thirty-six mice were fed an experimental diet for 10 weeks-a high-carbohydrate (HC) diet, a low-carbohydrate (LC) diet, or a control (C) diet. After 1 week on the experimental diets, mice were divided into sedentary and exercise groups (n = 6/group), where the exercise consisted of treadmill running for 30 min/day at 11 m/min for 6 days/week in 9 consecutive weeks. Intestinal sIgA levels in the exercise groups fed C or LC diets were significantly lower compared with the parallel sedentary groups, or exercise-group mice fed HC diet. Expression of the polymeric immunoglobulin receptor (pIgR) in the small intestine was significantly higher in the exercise group fed a HC diet. Superoxide dismutase activity in the small intestine was higher in the exercise group than in the sedentary group, with no effects resulting from intake carbohydrate levels. Our results indicated that moderate exercise reduced the levels of intestinal sIgA depending on decreasing of carbohydrate intake, which is connected with the expression of pIgR.
منابع مشابه
Favorable cardio-metabolic outcomes following high carbohydrate intake in accordance with the Daniel Fast: A review of available findings
The Daniel Fast is a biblically inspired dietary program rich in carbohydrate, most closely resembling a vegan diet but with additional restrictions, including the elimination of processed foods, white flour products, preservatives, additives, sweeteners, caffeine, and alcohol. While no specific requirements are placed on the ingestion of specific percentages of macronutrients, the mean daily c...
متن کاملEvaluation of the relationship between growth status and dietary intake in 10 children with thalassemia major
Introduction: Thalassemia major is the most common inheritable disease in Iran with high prevalence in Fars province. Growth retardation is prevalent in this patients, mainly due to malnutrition. The aim Goal of this study was to determine the relationship between growth status and nutritional intake. Patients under 10 years old with thalassemia major. Methods: In this cross-sectional stu...
متن کاملوضعیت تغذیهای در بیماران دیابتی نوع 1 و مقایسه آن با گروه کنترل
Background: The goal of dietary recommendations in children with type 1 diabetes mellitus is to achieve moderate to good control of blood glucose regarding to decrease in diabetic long-term complications. Although educational programs on appropriate dietary habits are offered in Isfahan Endocrine and Metabolism Research Center for diabetic patients, there is no information about their dietar...
متن کاملModerate dose of watercress and red radish does not reduce oxygen consumption during graded exhaustive exercise
Objective: Very recent studies have reported positive effects of dietary nitrate on the oxygen consumption during exercise. This research aimed to study the effect of moderate dose of high-nitrate vegetables, watercress (Nasturtium officinale) and red radish (Raphanus sativus) compared with a control group on the incremental treadmill exercise test following a standard Bruce protocol controlled...
متن کاملEffect of Moderate Swimming Exercise on Weight Gain in High Fat Diet Rats
Purpose: Obesity is one of the most common problems in the world. Imbalance between energy consumption and expenditure is a main factor in weight disorder. Exercise helps losing weight by increasing energy expenditure and modulation of the energy intake. The present study examined protective effects of daily moderate aerobic exercise on preventing weight gain in high fat diet rats. Materia...
متن کامل